The importance of Vitamin D and health
Read the article about vitamin D defiency
References :
1. The Role of Vitamin D in Cancer Prevention
2. Scientific documentation of the relationship of vitamin D deficiency and the development of cancer
3. The Role of Vitamin D in Brain Health: A Mini Literature Review
4. Emerging Role of Vitamin D and its Associated Molecules in Pathways Related to Pathogenesis of Thrombosis
5. Vitamin D Deficiency and Diabetes Mellitus
6. Exploring vitamin D metabolism and function in cancer | Experimental & Molecular Medicine
7. Op-Ed: Don't Let COVID-19 Patients Die With Vitamin D Deficiency | MedPage Today
8. Analysis of vitamin D level among asymptomatic and critically ill COVID-19 patients and its correlation with inflammatory markers
9. Does Vitamin D Deficiency Lead to Hypertension?
10. Vitamin D and Sunlight: Strategies for Cancer Prevention and Other Health Benefits | American Society of Nephrology
11. The importance of vitamin D levels in autoimmune diseases
12. Vitamin D From the pro-hormone to the biological actions : Acta portuguesa de nutricao
13. Vitamin D deficiency and depression in adults: systematic review and meta-analysis
14. Vitamin D deficiency and psychological disorders
15. Calcifediol treatment and COVID-19-related outcomes
16. A brief history of vitamin d and cancer prevention - PubMed
17. Effectiveness of Adding a Mask Recommendation to Other Public Health Measures to Prevent SARS-CoV-2 Infection in Danish Mask Wearers
18. The prevalence and determinants of vitamin D deficiency in Indonesian infants at birth and six months of age
19. COVID-19 treated by Vitamin D - studies, reports, videos | VitaminDWiki
20. Vitamin D: The Immunologic Role and its Effect on Human Pathophysiology
21. COVID-19 studies, HCQ, Ivermectin, Vitamin D, Zink etc.
22. Vitamin D accelerates clinical recovery from tuberculosis: results of the SUCCINCT Study
23. Impact of vitamin D on infectious disease-tuberculosis-a review - ScienceDirect
24. Epidemic influenza and vitamin D
25. ITP and Vitamin D + Hydroxychloroquine
26. On the epidemiology of influenza | Virology Journal
27. Vitamin D deficiency in children with acute bronchiolitis - BMC Pediatrics
28. Inverse Correlation between 25-OH Vitamin D Levels and Severity of Viral Respiratory Illness in Infants
29. Low Serum Vitamin D Levels Are Related to Life-Threatening Respiratory Syncytial Virus Infection in Previously Healthy Infants
30. Vitamin D: The "sunshine" vitamin
31. TUBERCULOSIS AND VITAMIN D DEFICIENCY IN KERALA, INDIA
32. The interplay between vitamin D and viral infections
33. Vitamin D-regulated Gene Expression
34. Vitamin D-Cathelicidin Axis
35. Vitamin D and Immune Regulation
36. The Vitamin D Receptor: New Paradigms for the Regulation of Gene Expression by 1,25-Dihydroxyvitamin D3
37. Cell Defenses and the Sunshine Vitamin
38. Maternal Vitamin D Prevents Abnormal Dopaminergic Development and Function in a Mouse Model of Prenatal Immune Activation
39. Cod liver oil in history of medicine
40. Cod Liver Oil: A Historical Perspective
41. Cod Liver Oil - A Short History & It's Benefits
42. Vitamin D Modulation of the Innate Immune Response to Paediatric Respiratory Pathogens Associated with Acute Lower Respiratory Infections
43. COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3
44. Five years' experience with hemo-irradiation according to the Knott technic
45. DISAPPEARANCE OF HEMOLYTIC STAPHYLOCOCCUS
AUREUS SEPTICEMIA FOLLOWING ULTRAVIOLET
BLOOD IRRADIATION THERAPY
46. Ultraviolet blood irradiation therapy: Further studies in acute infections
47. Ultraviolet Irradiation of Blood: "The Cure That Time Forgot"?
48. UVB Historia
49. Irarradiation therapy
50. Beneficial effects of UV radiation other than via vitamin D production
51. Koch's Postulates, Carnivorous Cows, and Tuberculosis Today
52. Koch's Postulates-Then and Now
Vitamin D deficiency, a ticking bomb?
In the 18th and 19th centuries, the world was plagued by a pandemic, Rickets, a disease that, among other things, led to skeletal deformity in especially young children. In the early 20th century, it was discovered that the cause was a lack of vitamin D and treatment with sunlight and cod liver oil had a curative effect.
Since then, we have learned a lot about the importance of Vitamin D and health. As a retired endocrine surgeon, I considered myself competent to do a literature review and the result of this was to some extent frightening, but also hopeful.
Scary because Vitamin D deficiency is still so common. In Portugal, for example, 30-60% of adults have a deficiency (study from 2017).
Scary because of the amount of disease this deficiency can potentially lead to.
Hoping because of how easy it would be to fix the problem.
Vitamin D is a vital prehormone that plays a major role in many of the body's processes. Almost all cells have a Vitamin-D receptor, a small "antenna" where the vitamin can attach to perform its functions. In addition to rickets and osteoporosis in adults, vitamin D deficiency is associated with a variety of diseases.
High blood pressure, cardiovascular disease, type 1 and type 2 diabetes mellitus and development of blood clots. Vitamin D deficiency is also associated with several autoimmune diseases such as MS and rheumatoid arthritis. And many more ailments are more common in people with vitamin D deficiency.
The vitamin is essential for our DNA repair system and for our mental health.
Deficiency can cause fatigue, depression, Alzheimer's, Autism, even psychosis. It is also important for the function of our immune system against cancer, invading bacteria and toxins as well as viruses. A very strong relationship is seen between vitamin D deficiency and severe morbidity and death in Covid-19. According to a new Spanish study, 60% more survived, and 80% were able to avoid intensive care, with vitamin D treatment alone.
Our main sources of Vitamin-D are the sun's ultraviolet rays (which ironically are often referred to as the sun's harmful radiation) and our diet, especially fat fish, eggs, red meat and more. In many countries, Vitamin D is added to certain products such as milk. However, there are no recommendations for this in Portugal. Children from 2 weeks to 1 year are recommended supplements here, but 31.7% do not take it for some reason.
Certain diets, especially high-fructose corn syrup, inhibit the activation of Vitamin D. Corn syrup is used in a variety of readymade products such as cakes, bread, cerials, sweets, soft drinks, etc. Sunscreen products prevent UV radiation from penetrating the skin and thus the production of the vitamin. Studies show a much higher frequency of Vitamin D deficiency in winter, and how far from the equator we are.
So why a ticking bomb in the headline?
Vitamin D deficiency was a pandemic even before the current restrictions. Dark-skinned people in northern latitudes, the overweight and the elderly are more vulnerable. We have now in most of the past year been banned from going to the beach and constantly urged to stay at home. We are encouraged to cover the last small sun-exposed part of our skin with a mask, despite the fact that the only larger randomized study from Denmark could not show any positive effect of a face mask, regarding spread of the virus.
I have not seen any major effort on the part of the authorities to call for vitamin D supplements or substitution of other vitamins or minerals for that matter. On top of all the other hugely negative effects of the shutdowns, I´m confident that this is a ticking health bomb.
I have tried to write this text short, simple and in a layman´s terms.
For those who are interested, I have gathered all the scientific basis for the above at:
Nils-Ola Holtze
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